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环孢素眼液治疗继发性Sjogren综合征干眼患者的临床分析

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摘要 Sjogren综合征(Sjogren syndrome,SS)是一种主要累及外分泌腺体的慢性自身免疫性疾病,多见于中老年女性,眼部表现为泪液分泌功能障碍导致的干眼。SS患者的眼部组织病理学显示大量淋巴细胞浸润泪腺和结膜组织(以T细胞为主),而活体激光共焦显微镜观察进一步发现其角膜中央可见大量郎格尔汉斯细胞(Langerhans cells,LCs)分布。SS分为原发性和继发性两类,
出处 《中华眼科杂志》 CAS CSCD 北大核心 2010年第5期456-458,共3页 Chinese Journal of Ophthalmology
基金 卫生部临床学科重点项目(2007-2009) 上海市市级医院新兴前沿技术联合攻关项目(SHDCI2007104)
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