无创机械通气治疗Ⅰ型呼吸衰竭63例临床研究

The clinic study of Non-invasive positive pressure ventilation (NIPPV) on 63 cases with typeⅠ respiratory failure

目的:探讨无创机械通气在Ⅰ型呼吸衰竭患者中的临床应用。方法:将119例IⅠ型呼吸衰竭患者随机分为治疗组与对照组,治疗组63例,在常规药物治疗的基础上给予机械勇气,对照组56例给予常规药物治疗,两组患者如上述治疗无效则采用气管插管行有创机械通气治疗。对比两组患者如治疗前后氧分压(PO2)、二氧化碳分压(PCO2)、血氧饱和度(SpO2)、插管率、总住院时间、住院总花费。结果:经治疗后两组患者动脉血PO2及SpO2较治疗前均有显著改善(P<0.05),而动脉PCO2治疗前后无显著性变化(P>0.05),治疗后NIPPV治疗组的PO2、SpO2较对照组比较升高更明显(P<0.05),治疗组患者的插管率、总住院时间、住院总花费均显著低于对照组(P<0.05)。结论:无创机械通气在救治呼吸衰竭时可以明显改善患者血气指标,减轻患者痛苦,缩短住院时间,降低医疗费用。

Objective：To investigate clinical application of the NIPPV on patient with Ⅰtype respiring failure.Methods：119 patients with typeⅠrespiratory failure were divided into two groups randomly.63 patients were given NIPPV and regular drug treatment in treatment group and 56 patients were only given regular drug treatment in control group.The patients were given invasive mechanical ventilation with intubation if above treatment were failure.The patients＇ blood gas analysis,oxygen saturation,intubation rate,total length of stay and total hospital costs were contrasted.Results：Patients＇ PO2 and SpO2 increased significantly alter treatment in two groups（P0.05）.Patients＇ PCO2 was no significant changed before and after treatment（P0.05）.Patients＇ PO2 in NIPPV group increased significantly contrasted with control group（P0.05）.And patients＇ intubation rate,total length of stay and total hospital costs in NIPPV group decreased significantly contrasted with control group（P0.05）.Conclusion：In clinical during treatment stage of I type respiratory failure,NIPPV can not only improve the patient＇s blood gas and life quality but also decrease the mortality,time and costs in hospital.