糖调节受损、新诊断2型糖尿病患者抑郁患病调查与相关因素分析

The prevalence and its related factors of depression in patients with IGR and newly diagnosed T2DM

目的探讨糖调节受损(IGR)、新诊断2型糖尿病(T2DM)患者抑郁患病情况及相关危险因素。方法从青岛湛山社区糖尿病流行病学数据库中随机选取正常糖耐量(NGT)、IGR、新诊断T2DM患者各150例进行抑郁状态评定。结果新诊断T2DM患者19.3%出现抑郁状态,而IGR组为10.7%。IGR组运动、年龄、BMI、性别、饮酒与抑郁指数显著相关,新诊断T2DM组HbA_1c、FPG、2hPG、性别、运动、年龄、受教育程度、高血压病史与抑郁指数显著相关(P<0.05或P<0.01)。结论 IGR人群和新诊断T2DM患者的抑郁状态应引起重视。

Objective To investigate the prevalence and risk factors of depression in patients with different glucose tolerant level. Methods Depression was evaluated in patients with NGT （n=150）, IGR （n=150） and T2DM （n= 150）. Results In IGR group, exercise, age, BMI, sex, drinking were correlated with depression index （P〈0. 05 or P〈0. 01）. In T2DM group, HbA1 c, FPG, 2hPG, sex, exercise, age, education, and history of hypertension were correlated with depression index（P〈0. 05 or P〈0. 01）. Conclusions It is necessary to pay a great attention to depression in patients with IGR and newly diagnosed T2DM.