非典型川崎病的临床特点及随访结果分析

目的:探讨非典型川崎病的临床特点及其冠脉损害的随访结果,提高对易于误诊和漏诊的非典型川崎病的早期诊断率,更好把握其治疗时机,减少严重并发症的发生。方法:回顾性分析1999年4月～2008年3月诊断为川崎病患儿68例临床症状及实验室检查。结果:23例仅持续发热>5天,双侧球结膜充血,口唇鲜红皲裂,恢复期指(趾)端脱皮或皮疹,颈部淋巴结肿大临床表现中的1或2、3项,但伴有多脏器损害。随访结果与典型川崎病比较,两者遗留冠脉损害并无显著差异。结论:对持续发热患儿注意排除川崎病,减少因对该病认识不足而延误治疗所造成的并发症。

Objective：To understand the clinical features of atypical Kawasaki disease and its follow - up results of coronary artery damage, raising early diagnosis of atypical Kawasaki disease, a better grasp of their treatment time to reduce the serious complications of the disease. Methods ： Section from 68cases of Kawasaki disease in children with clinical symptoms signs, laboratory tests were analyzed retrospectively. Results：Only 23 cases of persistent fever more than 5 days, bilateral conjunctival congestion, red lips, chapped, recovery means （ toe ） end of peeling, rash, clinical manifestations of cervical lymph node enlargement in one or two, three, but accompanied by multiple organ damage. Follow -up results compare with the typical left coronary artery lesion of Ka- wasaki disease is not significant. Conclusion： Children with persistent fever to rule out the disease, reduce disease due to lack of knowledge caused by delayed treatment of complications.