调节性T细胞在肿瘤免疫中的作用
摘要
近年来，国内外对调节性T细胞（regulatory T cells，Treg）的研究逐步扩展到其在肿瘤免疫中的作用，并由此引发出针对调节性T细胞的肿瘤免疫治疗。越来越多的证据表明在实体肿瘤和恶性血液病中调节性T细胞的数量是升高的，但我们仍对这一现象背后的机制知之甚少；而且除了FOXP3，我们缺少对Treg更特异的标记的发现。因此，深入认识Treg细胞及其在抑制抗肿瘤免疫中的作用，将有助于提高肿瘤免疫治疗的效果。
出处
《国际耳鼻咽喉头颈外科杂志》
2010年第2期115-118,共4页
International Journal of Otolaryngology-Head and Neck Surgery
基金
北京市卫生局、北京市中医管理局青年科学研究资助项目（QN2008-024）
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