61例肺结核影像学表现及血清腺苷脱氨酶检测

Imageological manifestation and determination of serum adenosine deaminase in patients with pulmonary tuberculosis

目的:分析近期肺结核的临床表现、影像学特点,探讨肺结核各期与血清腺苷脱氨酶的关系。方法:回顾性分析61例肺结核患者的临床表现、胸部X线及CT扫描特点;将所有病例按活动性及转归分为进展期、好转期、稳定期,另随机抽取20例正常志愿者做对照组,分析比较各组血清腺苷脱氨酶水平。结果:61患者均符合肺结核的临床表现和(或)影像学等特点,进展期24例,好转期16例,稳定期21例,血清腺苷脱氨酶水平检测结果显示进展期和好转期患者血清腺苷脱氨酶水平较稳定期及对照组高(P<0.01),且进展期血清腺苷脱氨酶水平高于好转期((P<0.05),稳定期与对照组比较,血清腺苷脱氨酶水平统计无显著差异(P>0.05)。结论:影像学检查是肺结核诊断的基本手段;血清腺苷脱氨酶检测可考虑作为肺结核的辅助诊断之一。

Objective：To analyze the clinical manifestation and imageological feature of the recent tuberculosis,investigate the relation between stages of pulmonary tuberculosis and serum adenosine deaminase.Methods：These clinical datum of 61 patients with pulmonary tuberculosis were analyzed retrospectively,including their clinical manifestation,imageological feature of chest X-ray and computed tomographic（CT） screening.According to activity and prognosis,all cases were divided into progressive,resolving and stable stage;moreover,the other 20 normal volunteers were randomly selected as control group,to analyze the level of serum adenosine deaminase between groups.Results：Sixty one patients had clinical manifestation and（or） imageological feature of tuberculosis,included 24 cases in progressive stage,16 cases in resolving stage and 21 cases in stable stage.Results of serum adenosine deaminase showed levels of adenosine deaminase in patients with progressive or resolving stage were higher than those with stable stage or the control group（P0.01）,and the levels in those with progressive stage were higher than those with the resolving stage（（P 0.05）,compared with the control group,the levels in patients with stable stage were no significant statistical difference（P0.05）.Conclusion：The Imageological examination is a basic way for the diagnosis of pulmonary tuberculosis.Determination of serum adenosine deaminase may be considered as one of ways for the diagnosis of pulmonary tuberculosis.