摘要
目的探讨结肠镜随访对大肠癌术后复发的临床意义。方法自2000年1月至2008年12月,对138例大肠癌术后患者进行结肠镜随访检查,发现可疑病变取活检,发现息肉则行镜下凝固治疗,秩和检验进行随访结果统计分析。结果 138例患者检出复发癌12例,其中男性10例,女性2例,两者差异显著(P<0.05);升结肠2例,横结肠1例,降结肠2例,乙状结肠3例,直肠4例,三者之间无差异(P>0.05);其中吻合口复发癌8例,原发癌4例,治疗息肉22例,共36枚,其中腺瘤性息肉26例、吻合口炎10例。12例复发癌患者中,正规随访者11例,未正规随访者仅1例,两者差异显著(P<0.001);术后2年内复发11例,1例发生于3.5年,差异显著(P<0.001)。结论大肠癌术后2年内常规进行结肠镜检查可早期发现复发病灶,并可切除腺瘤性息肉,对降低大肠癌复发具有较大的临床价值。
Objective To discuss the clinical value of colonoscopy follow-up on the postoperative re-currence of colon cancer.Methods From 2000.Jan to 2008.Dec, 138 cases of colorectal cancer were postoperatively followed-up by colonoscopy, with suspicious lesions biopsy, polyps being coagulated, rank sum test for statistical analysis.Results 12 of 138 cases were relapsed in colorectal cancer, with 10 cases of men, and 2 cases of women, in significant difference (P〈0.05); the cancer situs were ascending colon of 2 cases, transverse colon of 1, descending colon of 2, sigmoid colon of 3, the rectum of 4 cases, were in no difference among them(P〉 0.05); 8 cases were anastomotic cancer, other 4 cases in situ; 36 polyps in all of 22 patients were treated, with 26 adenomatous polyps, 10 cases of anastomotic inflammation. 11 of 12 relapsed cases were regularly followed-up, while only 1 case in group without regular following-up , in significant differences (P〈0.001); 11 cases recurred within 2 years after surgery, while 1 case in 3.5 years postoperatively, that was significantly different (P〈0.001).Conclusion Conventional colonoscopy within 2 years postoperatively is important for the early detection of recurrent lesions, and removal of adenomatous polyps to reduce the recurrence of colorectal cancer have greater clinical value.
出处
《中国实用医药》
2010年第15期67-69,共3页
China Practical Medicine
关键词
大肠癌
结肠镜
随访
复发
Colorectal cancer
Colonoscopy
follow-up
Recurrence