偶极子核磁融合定位病灶与致痫灶及术中导航系统的应用

Localization of Epileptogenic Zone and Lesion Area Using EEG Dipole and MRI Fusion Under Neuronavigation System

探讨脑电偶极子与头MRI融合定位致痫灶及病灶并在术中导航引导下切除的方法。回顾性分析2006年6月至2009年3月期间玉泉医院癫痫中心收治的10例行手术治疗癫痫病例,行头MRI明确病灶,并用脑电偶极子定位致痫灶,术中导航引导下切除病灶及癫痫灶。10例病例行手术切除病灶及癫痫灶,无手术死亡及严重并发症。随访6～36个月。手术后疗效按Wilson标准评判,优良率为84%,7例(70%)癫痫发作完全消失;2例(20%)癫痫发作次数显著减少;1例(10%)无明显改善。由此得出结论:脑电偶极子及头颅MRI联合应用,明确病灶及癫痫灶,并在导航引导下切除病灶及癫痫灶治疗癫痫是精确有效的方法。

To study the localization of epileptogenic zone and lesion area using EEG dipole and MRI fusion and then resection with help of neuronavigation,10 cases were analyzed for patients who received surgery treatment for epilepsy with brain lession in our ward during the period of June,2006 to March,2009. Scanning of MRI and EEG dipole localization was performed for all those patients,then the lession and epileptogenic zone were removed using neuronavigation system. There was no severe complication mortality. Patients were followed up for a duration from 6 months to 36 months. The curative effect is judged with Wilson standard in postop,and it is found that the fineness rate is 90%,7 cases （70%） are free from seizure,2 cases（20%） see a significant reduction of seizure attack ,only 1 case （10%） sees no significant change. It is concluded that the localization of epileptogenic zone and lesion area with EEG dipole and MRI fusion and then the resection with help of neuronavigation are reliable method for refractory epilepsy with brain lession.