癫痫患者的智力水平及相关因素研究

A study of intelligence status and affecting factors in epilepsy patients

目的探讨癫痫患者的智力水平及相关因素。方法对53例癫痫患者采用修订的韦氏成人智力量表（WAIS—RC）进行测评，并以53名正常人作为对照，应用自制的癫痫患者人口学及相关资料调查表进行相关因素调查。结果癫痫患者言语智商、操作智商和总智商[分别为（68．17±8．58）分，（67．40±10．05）分，（65．04±9．45）分]，低于对照组[分别为（106．31±10．25）分，（108．45±11．34）分，（107．42±11．03）分]，差异具有显著性（P=0．000）。逐步回归分析揭示，影响言语智商的主要因素为发作频率、文化程度及癫痫的病因分类；影响操作智商的主要因素为发作频率及文化程度；影响总智商的主要因素为发作频率、文化程度及脑外伤或脑炎史。结论癫痫患者的智力水平较低，其影响因素涉及多个方面。

Objective To study intelligence status and affecting factors in epilepsy patients. Methods Fifty three patients and the same number of normal controls were evaluated with Wechsler Adult Intel- ligence Scale（ WAIS-RC）, and the related factors were investigated with self-made questionnaires. Results The verbal intelligence quotient （ VIQ ）, performance intelligence quotient （ PIQ ） and full-scale intelligence quotient （FIQ） were （68.17 ± 8.58 ）, （ 67.40 ± 10.05 ）, （65.04 ± 9.45 ） respectively, lower than those of normal controls （ 106.31 ±10.25 ）, （ 108.45 ± 11.34 ）, （ 107.42 ± 11.03 ） respectively. Main influencing factors contributing to VIQ were frequency of epileptic seizure, education level and etiological classification of epilepsy. Main influencing factors contributing to PIQ were frequency of epileptic seizure and education level. Main influencing factors con- tributing to FIQ were frequency of epileptic seizure, education level and history of traumatic brain injury or enceph- alitis. Conclusion Intelligence status is lower in epilepsy patients and its influencing factors are related to many respects.