Rb94基因在恶性肿瘤中的研究进展

Research advances of Rb94 gene in malignant tumors

视网膜母细胞瘤基因（Rb94）与野生Rb110基因相比具有更强的肿瘤抑制效应。Rb94基因转染肿瘤细胞后可调节端粒酶活性，诱导细胞凋亡，调控细胞周期，与放、化疗联合可起到协同作用。

Retinoblastoma 94 （RB94）gene, a new tumor suppressor gene, is found in the past several years. It has been found that Rb94 gene has a more powerful antitumor effection compared with Rb110 gene. After transfection, Rb94 gene could adjust telomerase activation, induce apoptosis and regulate cell cycle. It also has a synergistic action associated with radiotherapy or chemotherapy.