摘要
目的探讨有独立测压管的双水平气道正压(bi-level positive airway pressure,BiPAP)无创呼吸机治疗老年慢性阻塞性肺疾病急性加重期(acute exacerbations of chronic obstructive pulmonary disease,AECOPD)合并Ⅱ型呼吸衰竭(呼衰)的效果。方法回顾性分析43例老年AECOPD合并Ⅱ型呼衰采用无创呼吸机治疗的临床资料,根据呼吸机有无独立测压管分为A、B两组,比较两组治疗24 h后无创通气的有效率及治疗前后动脉血气分析值的变化。结果无创呼吸机治疗24 h后,A组有效20例,有效率90.91%;B组有效16例,有效率76.19%,两组有效率比较差异有统计学意义(χ2=7.8400,P=0.0051);组间比较,两组治疗后的pH和氧分压(PaO2)值较治疗前升高,二氧化碳分压(PaCO2)较治疗前下降;治疗后A组pH7.42±0.03,PaO2(69.38±5.17)mmHg,PaCO2(63.39±7.54)mmHg,与B组比较差异均有统计学意义(P<0.01)。结论有独立测压管的BiPAP无创呼吸机治疗AECOPD合并Ⅱ型呼衰疗效确切,优于无独立测压管的BiPAP无创呼吸机。
Objective To discuss the clinical effects of the treatment of type Ⅱ respiratory failure of senile patients with acute exacerbations of chronic obstructive pulmonary disease(AECOPD) by independent pressure-testing BiPAP(bi-level positive airway pressure) non-invasive positive pressure ventilator.Methods 43 senile patients with AECOPD with type Ⅱ respiratory failure were divided into group A and group B according to whether the ventilator was equipped with independent pressure-testing pipe or not and were retrospectively analyzed.The efficiency of the two groups within 24 hours of the treatment of non-invasive ventilation and the changes of arterial blood gas analysis before and after ventilation were compared.Results 24 hours after the treatment with non-invasive ventilator,20 patients from Group A showed improvement and the efficiency rate was 90.91%;16 patients from group B showed improvement and the efficiency rate was 76.19%.The efficiency difference between the two groups was statistically significant(χ2=7.8400,P=0.0051);intra-group comparison indicated that,after the treatment,the value of pH and PaO2 of both the two groups increased,while the value of PaCO2 decreased.After the treatment,pH 7.42±0.03,PaO2(69.38±5.17)mmHg,PCO2(63.39±7.54) mmHg of group A showed significant difference when compared with that of group B(P0.01).Conclusion The curative effects of the treatment of AECOPD with type Ⅱ respiratory failure by independent pressure-testing BiPAP non-invasive positive pressure ventilator are significant.The one with independent pressure-testing is superior to that without it.
出处
《临床误诊误治》
2010年第5期410-412,共3页
Clinical Misdiagnosis & Mistherapy
关键词
肺疾病
慢性阻塞性
并发症
呼吸功能不全
无创呼吸机
Chronic obstructive pulmonary disease
Complication
Respiratory insufficiency
Non-invasive positive pressure ventilator