牙膏抑菌效果分析研究

Research on Antibacterial Properties of Toothpastes

初步研究牙膏对大肠杆菌、金黄色葡萄球菌、绿脓杆菌三种比较常见致病菌的抑制效果,检验牙膏抑菌合格与否。用"抗菌有效性"方法,研究LP、MP、HP、LP-HE、LP-BA五种牙膏抑菌效果。LP牙膏中三种细菌浓度维持在106cfu/mL以上,其余四种牙膏在第14天后没有细菌生长,其中MP在4个周期5次检验中都没有细菌生长,LP-BA有类似抑菌效果,但第2次检验时,金黄色葡萄球菌和大肠杆菌的浓度分别为4×104cfu/mL和35×104cfu/mL,HP与LP-H有类似抑菌效果,在第2次检验时仅大肠杆菌生长,细菌浓度分别为1×106cfu/mL和2×106cfu/mL。LP牙膏不能对实验细菌起到抑制作用,而其余四种牙膏能有效的抑制细菌增长。

The antibacterial activity of toothpastes were examined against Staphylococcus aureus,escherichia coli and pseudomonas aeruginosa,to judge whether toothpaste meet GB.Using antimicrobial effectiveness test to preliminary study on the antibacterial properties of toothpaste（LP,MP,HP,LP-HE,LP-BA）,three bacterial concentration of LP were over 106cfu/mL,the others had no growth of bacteria after 14 days,and MP had no growth of bacteria within the 28 days,LP-BA was similar inhibitory effect,but the concentrations of escherichia coli and staphylococcus aureus were 4×104cfu/mL,35×104cfu/mL respectively,as 2nd test,HP and LP-H were similar inhibitory effect,only the concentration of escherichia coli was 1×106cfu/mL,2×106cfu/mL when 2nd test.The LP had no antibacterial property,and the other four toothpastes could effectively inhibit bacterial growth.