玉竹中的四个高异黄酮(英文)

Four Homoisoflavanones from Polygonatum odoratum

目的:研究玉竹的化学成分。方法:运用各种分离方法(硅胶柱层析,SephadexLH-20)分离化合物,根据理化性质和波谱数据鉴定化合物的结构。结果:从玉竹中分离并鉴定了4个高异黄酮类化合物,结构分别为(±)5,7-dihydroxy-3-(2-hydroxy-4-methoxybenzyl)-6,8-dimethylchroman-4-one(1),(3R)-5,7-dihydroxy-3-(4-hydroxybenzyl)-6,8-dimethylchroman-4-one(2),(3R)-5,7-dihydroxy-3-(4-hydroxybenzyl)-8-methoxy-6-methylchroman-4-one(3),(3R)-5,7-dihy-droxy-3-(4-hydroxybenzyl)-6-methylch-roman-4-one(4)。结论:高异黄酮类化合物在自然界很少见。

AIM：To study the chemical constituents from the rhizome of Polygonatum odoratum（Mill.） Druce.METHODS：The chemical constituents were isolated by chromatographic separations of silica gel and Sephadex LH-20 and their structures were elucidated on the basis of spectral analysis.RESULTS：Four homoisoflavanones were isolated and identified as（±）5,7-di-hydroxy-3-（2-hydroxy-4-methoxybenzyl）-6,8-dimethylchroman-4-one（1）,（3R）-5,7-dihy-droxy-3-（4-hydroxybenzyl）-6,8-dimethylchroman-4-one（2）,（3R）-5,7-dihydroxy-3-（4-hydroxybenzyl）-8-methoxy-6-methylchroman-4-one（3）,and（3R）-5,7-dihydroxy-3-（4-hydroxybenzyl）-6-methyl-chroman-4-one（4）.CONCLUSION：Homoisoflavanones were rare in nature.