K_5CoW_(12)O_(40)·3H_2O催化合成苯甲醛1,2-丙二醇缩醛

Synthesis of Benzaldehyde 1,2-Propylene Acetal Catalyzed by K_5CoW_(12)O_(40)·3H_2O

研究了K5CoW12O40.3H2O催化剂对苯甲醛和1,2-丙二醇为原料合成苯甲醛1,2-丙二醇缩醛的反应的催化活性。考察了醛醇物质的量比、催化剂质量、带水剂体积、反应时间、催化剂重复使用性等因素对产品收率的影响。结果表明,K5CoW12O40.3H2O是缩醛反应的良好催化剂。在最佳实验条件下:苯甲醛与1,2-丙二醇物质的量比为1:1.2、苯甲醛物质的量为0.1mol、催化剂质量为0.3g、环己烷体积为10mL、反应时间45min,苯甲醛1,2-丙二醇缩醛的收率最高可达92.8%。

The catalytic activity of benzaldehyde 1,2-propylene acetal was investigated from benzaldehyde and 1,2-propylene glycol in the presence of potassium dodecatungstocobaltate trihydrate （K5CoW12O40·3H2O）.The effects of the cyclohexanone/1,2-propylene glycol molar ratio,the amount of the catalyst,cyclohexane dosage,the reaction time and the using regenerated catalyst on yield were studied systematically.The results show that potassium dodecatungstocobaltate trihydrate （K5CoW12O40·3H2O） is an excellent catalyst for the above reaction.The preferable experimental conditions are as follows：benzaldehyde/1,2-propylene glycol molar ratio is 1：1.2,benzaldehyde is 0.1 mol,potassium dodecatungstocobaltate trihydrate （K5CoW12O40·3H2O） is 0.3 g,the volume of cyclohexane is 10 mL,and reaction time is 45 min.Under the above experimental conditions,the maximum yield of benzaldehyde 1,2-propylene acetal is up to 92.8%.