异种移植与中国地方猪种资源的利用

PRELIMILARY EVALUATION OF XENOTRANSPLANTATION AND UTILIZATION OF NATIVE PIG BREEDS IN CHINA

目的了解中国地方猪种资源概况及研究现状，使之更好地为异种移植服务。方法通过比较猪与非人灵长类动物在异种移植上的优劣及当前异种移植界对猪种资源的重视，分析中国地方猪种在异种移植供体选择上是否存在优势。结果中国是猪种资源最丰富的国家之一，猪种多样性和遗传相对稳定性为异种移植提供了可贵的研究和利用资源，而异种移植又为猪种的利用提供了机遇。结论中国地方猪种资源可能会引起世界异种移植界的重视，在其保护与利用。

Objective To evaluate the general situation of the native pig breeds and the relative present study conditions for better development of xenotransplantation in China. Methods By comparing the profits between the pigs and the non human primates as the potential donors for xenotransplantation and emphasizing the source of the pigs as the organ donors from the transplantation studies, we analyzed the possible values of the native pig breeds as the donors. Results As one of the richest resources in the world, the species variation and relative genetic stability of Chinese native pig breeds could be the very valuable resources for xenotransplantation study and utilization. As a reverse, the xenotransplantation could provide opportunity for more economically and environmentally utilization of the pigs besides as the meat supply. Conclusion As a very valuable and potential resource of organ donor, the native pig breeds of China might be noticed by the xenotransplantation colleagues in the world. It is necessary, to keep the balance among the risk vs. benefit and the protection vs. utilization of this valuable resource.