沙眼衣原体母婴垂直感染的研究

TO STUDY MOTHERS AND NEWBORNS VERTICAL INFECTION OF CHLAMYDIA TRACHOMATIS

探讨沙眼衣原体（Ｃｔ）母婴垂直感染问题。方法：用Ｃｔ单克隆抗体免疫酶（Ｃｔ－ＭｃＡｂ－ＨＲＰ）检测 １８～４９岁 １５０名已婚妇女和 １８～２６岁 １３２名孕妇宫颈分泌物。用 ＰＣＲ ｋ Ｃｔ－ＭｃＡｂ－ＨＲＰ两法检测 ５０例已婚妇女宫颈分泌物，进行阳性与阴性符合率比较。结果：Ｃｔ阳性率已婚妇女为 ２０．６７％，孕妇为 ２０．４５％。 ２７例 Ｃｔ阳性孕妇所生新生儿Ｃｔ阳性率为 ３７．０４％。１０５例 Ｃｔ阴性孕妇所生新生儿Ｃｔ阳性率为 １． ９０％，Ｐ＜０． ０１。结论：建议分娩前常规进行衣原体检测。

objective To investigate the infective rate of chlamydia trachomatis (Ct) be- tween mothers and newborns. Medthods The cervical swab samples were obtained from 150 married women (18-49 age) and 132 pregnant women (18-26 age) for the determination of Ct by monoclonal antibodies immune enzyme (Ct-McAb-HRP) and polymerase chain reaction (PCR). In the same time using the both methods of PCR and Ct-McAb-HRP to examined cervical swab samples of 50 married women for the accord with rate of positive and negative. Results The positive rate of Ct was 20. 67% in the 150 cases married women and 132 cases pregnant women positive rate was 20. 45%. 27 cases was positiive of pregnant women of their neonate found Ct infection rate was 37. 04%. but 105 cases of pregnant women were negative only 1. 90%, P<0. 05. Conclutions Propose that the before delivery conventional examine Ct of pregnant women.