摘要
目的:了解糖尿病患者血甲状旁腺素(PTH)、降钙素(CT)的变化及其临床意义。方法:观察59例糖尿病患者血PTH及CT的变化,与对照组比较。同时测定血肌酐、钙、磷、碱性磷酸酶。各组数据行方差分析、t检验、直线相关分析。结果:糖尿病患者除并发尿毒症外,血钙、磷正常。与对照组比较,并发糖尿病肾病者血PTH、CT升高(P<0.01)。并随着糖尿病肾病严重程度的加重而增加;与血肌酐呈正相关(P<0.001),与血碱性磷酸酶无相关性(P>0.05)。结论:糖尿病患者一旦发生糖尿病肾病,就存在血PTH、CT的异常及潜在的钙磷代谢紊乱。
Objective:To test the level change in parathyrin(PTH) and calcitonin(CT) in blood of diabetic patients.Methods:PTH and CT levels in 59 cases of diabetics were measured to compare with those in normal persons.The blood Cr,Ca 2+ ,P 3+ and AKP were tested simutaniously.The data were analysed by statistics.Results:Except in cases complicated with uremias,the diabetic patients had the normal concentration of Ca 2+ and P 3+ in blood;The blood PTH and CT rose in the patients complicated with nephropathy and increased as the nephropathy was getting more severe,and also correlated with the blood Cr( P <0.001),but not with the blood AKP level( P >0.05).Conclusions:Patient with diabetes occurs changes in blood PTH and CT in case complicated with nephropathy and has a potential disorden in Ca 2+ and P 3+ metabolism.
出处
《蚌埠医学院学报》
CAS
1999年第1期15-16,共2页
Journal of Bengbu Medical College
关键词
糖尿病
糖尿病肾病
甲状旁腺
降钙素
diabetes mellitus
diabetic nephropathies
aparathyroid hormones(PTH)
calcitonin(CT)