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心肌血管再生治疗技术的研究进展 被引量:4

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摘要 缺血性心脏病发病率、致死率较高,且大约10%左右弥漫性冠脉病变的患者仍得不到有效治疗。近年来,基因及干细胞技术的发展为缺血性心脏病的治疗提供了新的方向。随着研究的深入,除了血管再生机制取得突破外,新技术新方法也得到了快速的发展。比如:干细胞治疗、细胞因子治疗、基因治疗、激光心肌血运重建术治疗、超声靶向破坏微泡造影剂以及多种方法联合治疗。文章就心肌血管再生治疗的技术方法进行综述。
作者 周志益 黄晶
出处 《国际心血管病杂志》 2010年第3期129-131,165,共4页 International Journal of Cardiovascular Disease
基金 国家自然科学基金(10527004) 重庆市科技攻关计划(CSTS2009AB5003)
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  • 1王莉,俞春江,耿敬姝.缺氧诱导因子-1α、VEGF在进展期胃癌中的表达及意义[J].实用肿瘤学杂志,2005,19(5):337-340. 被引量:11
  • 2Zen K,Okigaki M,Hosokawa Y,et al.Myocardium-targeted delivery of endothelial progenitor cells by ultrasound-mediated microbubble destruction improves cardiac function via an angiogenic response.J Mol Cell Cardiol,2006,40(6):799-809.
  • 3Ji Song PhD,Ming Qi,BS Sanjiv Kaul,et a1.Stimulation of arteriogenesis in skeletal muscle by microbubble destruction with ultrasound.Circulation,2002,106:1550-1555.
  • 4Junji Yoshida MD,Kojiohmori MD PhD,Hiroto Takeuchi MD PhD,et al.Treatment of ischemic limbs based on local recruitment of vascular endothelial growth factor-producing inflammatory cells with ultrasonic microbubble destruction.J Am Coll Cardial,2005,46:899-905.
  • 5Kaygusuz G,Tulunay O,Baltaci S,et al.Mierovessel density and regulators of angiogenesis in malignant and nonmalignant prostate tissue[J].Int Urol Nephrol,2007,39(3):841-850.
  • 6Ahmet I,Sawa Y,Yamaguchi T,et al.Gene transfer of hepatocyte growth factor improves angiogenesis and function of chronic ischemic myocardinm in canine heart[J].Ann Thorac Stag,2003,75(4):1283-1287.
  • 7Ueda H,Nakamura T,Matsumoto K,et al.A potential car-dioprotective role of hepatocyte growth factor in myocardial infarction in rats[J].Cardiovasc Res,2001,51 (1):41-50.
  • 8Nakamura T,Mizuno S,Matsumoto K,et al.Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF[J].J Clin Invest,2000,106(12):1511-1519.
  • 9Taniyama Y,Morishita R,Nakagami H,et al.Potential contribution of a novel antitibrotic factor,hepatocyte growth factor,to prevention of myocardial fibrosis by angiotensin Ⅱ blockade in eardiomyopathie hamsters[J].Circulation,2000,102(2):246-252.
  • 10Zhigang W,Zhiyu L,Haitao R,et al.Ultrasound-mediated microbubble destruction enhances VEGF gene delivery to the infareted myocardium in rats[J].Clin Imaging,2004,28 (6):395-398.

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