支气管哮喘和慢性喘息型支气管炎患者发作期呼吸音的分析研究

Spectral analysis of breath sounds in asthmatics and chronic asthmatic bronchitis during episode

目的：探讨支气管哮喘和慢性喘息型支气管炎（慢喘支）患者发作期呼吸音的频谱特点，并对两者进行分析比较。方法：利用传感器和微型计算机等设备录取１０例发作期哮喘患者和８例发作期慢喘支患者的呼吸音，并对其进行快速付里叶转换（ＦａｓｔＦｏｕｒｉｅｒｔｒａｎｓｆｏｒｍ，ＦＦＴ）频谱分析。结果：发作期哮喘和发作期慢喘支患者产生喘鸣音时的呼气频率〔２组的最高峰处频率（ＰＦ）和曲线下面积４等份处频率（Ｑ２５％、Ｑ５０％和Ｑ７５％）分别为（３８８．４２±８２．４３）Ｈｚ、（３１２．９６±６６．８８）Ｈｚ、（４２２．２４±９１．１６）Ｈｚ、（５３８．７６±１１０．２２）Ｈｚ比（３５９．４３±４５．４６）Ｈｚ、（２９６．９８±６７．８４）Ｈｚ、（４２１．４３±９１．８２）Ｈｚ、（５２３．２９±６０．１６）Ｈｚ〕和呼吸音强度〔ＬＳＩ，分别为（２３．１８±０．８６）ｄＢ比（２３．１１±０．５６）ｄＢ〕无显著性差别（Ｐ均＞０．０５）；发作期慢喘支患者吸气时的频率比发作期哮喘患者低〔２组的ＰＦ、Ｑ２５％、Ｑ５０％和Ｑ７５％分别为（１７６．６８±３６．８４）Ｈｚ，（１７１．３２±３２．６４）Ｈｚ，（２２９．６９±３１．８７）Ｈｚ，（３８２．?

Objective:To evaluate and compare the spectral characteristics of the breath sounds in asthmatics and chronic asthmatic bronchitis during episode.Methods:The breath sounds in 10 asthmatics and 8 chronic asthmatic bronchitis during episode were recorded by using microphone and computer and analyzed with FFT (fastFourier transform).Results:The expiratory frequency and intensity between the wheezes in asthmatics PF=(388 42±82 43)Hz,Q25%=(312 96±66 88)Hz,Q50%=(422 24±91 16)Hz,Q75%=(538 76±110 22)Hz,LSI=(23 18±0 86)dB,respectively and chronic asthmatic bronchitis PF=(359 43± 45 46)Hz, Q25%=(296 98±67 84)Hz,Q50%=(421 43±91 82)Hz,Q75%=(523 29±60 16)Hz,LSI=(23 11±0 56)dB,respectively during episode were not marked different (all P >0 05) Chronic asthmatic bronchitis during episode PF=(176 68±36 84)Hz,Q25%=(171 32±32 64)Hz,Q50%=(229 69± 31 87)Hz, Q75%=(382 36±55 21)Hz,respectively had lower inspiratory frequencies than asthmatics during episode PF=(354 21±67 58)Hz,Q25%=(286 42±53 68)Hz,Q50%=(386 77±74 18)Hz, Q75%=(554 68 ± 84 72)Hz ,respectively, P <0 05 or P <0 01 .Conclusions:The results suggest that the analysis of the breath sounds in asthmatics and chronic asthmatic bronchitis during episode may be helpful for their diagnosis and differential diagnosis.