资源县368例儿童手足口病流行病学特征分析

Clinical epidemiological characteristics of hand-foot-mouth disease in 368 children in Ziyuan county

目的:对资源县2008年5月1日至2009年3月31日发病的儿童手足口病的临床流行病学特征进行分析,为防治该病提供理论依据。方法:对368例收治住院病例进行临床流行病学分析。结果:发病年龄以6岁以下(91%以上)多见,男性患儿多于女性,发病高峰为5～8月份,52.7%患儿发病前有流行病学接触史,临床表现典型,症状轻微,少数患儿并发脑膜脑炎、心肌损害、肺炎和肝功能损害,有9例重症,死亡1例。结论:手足口病只要早发现、早诊断、早隔离、早上报、早治疗,并给予足够的重视,患儿大部分预后良好。

Objective：To analyze the epidemiological and clinical characteristics of children with hand-foot-mouth disease（HFMD） in Ziyuan county area from May.in 2008 to Mar.in 2009,in order to prevent and treat diseases in the region and provide a theoretical basis.Methods：368 inpatients from May.in 2008 to Mar.in 2009 were investigated for epidemiological information and clinical features.Results：368 children were hospitalized.The prevalent peak was from May to Aug.Most （91%） of the HFMD children were 6 or below 6 years old.Most cases （52.7%） had a history of contacting with HFMD cases before onset of the disease.The clinical manifestations of inpatients who had fever,oral ulcers and vesicular rash appearing on the hands,feet,knees,and/or buttocks were typical and mild.The clinical complications occurred in some patients,including encephalitis or aseptic meningitis,myocardial injury,pneumonia and liver function injury.There were 9 severe and 1 fatal cases.Conclusions：The HFMD can be healed and prevented.The prognosis of HFMD was good if the disease could be early discovered,diagnosed and managed.