DNA损伤修复及细胞周期检控点激活的研究进展

The activation of DNA damage repair and cell cycle checking point

新近的研究结果使人们对DNA损伤诱导的细胞和分子事件，特别是与DNA损伤反应和损伤修复相关蛋白的激活以及在DNA损伤部位的募集，有了更深入的认识；对细胞周期检控点的激活以及随后的细胞周期调控有了进一步的理解。

There are more understandings on the DNA damage-induced cellular and molecular events, especially on the activation and recruitment of proteins responsible for DNA damage response and DNA damage repair to the site of damaged DNA. The activation of cell cycle checking point is more clearly elucidated on its mechanism and the subsequent cell cycle regulation.