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急性心肌梗死患者抗心磷脂抗体及相关因素分析

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摘要 目的:探讨急性心肌梗死(AMI)患者发病早期至1周内血清抗心磷脂抗体(ACA)、D-二聚体(D-D)、血小板第4因子(PF4)的动态变化及其相互关系。方法:测定46例AMI患者发病24 h和1周时血清ACA、D-二聚体、PF4并与健康对照组40例比较。结果:AMI患者发病24 h血清ACA、D-二聚体、PF4分别为1.14±0.18、1.21±0.29、1.01±0.28、358.3±62.1、5.8±1.38及1周时ACA、D-D、PF4分别为1.24±0.25、0.98±0.11、0.96±0.29、386.1±45.2、6.92±1.41均明显高于对照组,且它们之间均有正相关性(P<0.01)。结论:AMI从发病早期至1周内ACA、D-D、PF4持续增高,表明自身抗体ACA、凝血因子D-D、PF4参与血栓的形成,早期应用血栓药物,可防止AMI的病情进展。
作者 徐丽
出处 《中国误诊学杂志》 CAS 2010年第15期3578-3578,共1页 Chinese Journal of Misdiagnostics
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