酒精性肝病的遣方用药规律探析

Exploration of prescribing rules in alcoholic liver disease

通过对近5年中医辨证论治酒精性肝病的文献总结,从遣方用药的角度探讨中医药对于本病的认识及遣方用药规律。归纳用于治疗酒精性肝病的选药类别特点,并根据"以方测证"、"方证相应"的原理,总结酒精性肝病治疗法则及主要证素认识。结果表明活血化瘀、补益虚损、利水渗湿是近年来医家防治酒精性肝病的主要治疗法则,而血瘀、气虚、痰湿是酒精性肝病的主要病机。根据文献研究可以看出目前中医药治疗酒精性肝病研究尚处于临床观察探索阶段,缺乏多中心、随机对照的大样本的前瞻性研究,疗效判断不统一,缺乏客观评价标准。这些问题值得进一步探讨。

Summarizing the literature of syndrome differentiation and treatment of alcoholic liver disease （ALD） with Traditional Chinese Medicine （TCM） in recent five years,to investigate the realization and the laws of prescribing in this disease from the perspective of selecting drugs and forming formulas of TCM. This article summarized the characteristics of formula selection in treating ALD,and summed up the treatment principle of ALD and the realization of main syndrome by the principle of ＇learning syndrome from formula＇,＇correspondence of syndrome with for mula＇. The results showed that promoting blood circulation for removing blood stasis,tonifying consumption,promoting diuresis and percolating dampness were the main principle of prevention and treatment of ALD in recent years,and blood stasis,qi asthenia and phlegmatic hygrosis were the major pathogenesis of ALD. According to studying the literature of TCM,it was can be seen that the present treatment of ALD was still in the exploratory stage of clinical observation,it lacked multi-center,randomized and control prospective study of large sample,and judgment of curative effect were disunity,and objective evaluation criteria was lacked. These questions were worth further exploration.