摘要
目的检验茶多酚抗家兔实验性高脂血症及脂肪肝的影响。方法将20只健康雄性白兔随机分为4组(n=5),对照组给予基础饲料;模型组给予高脂饲料;茶多酚组给予高脂饲料同时分别灌胃200 mg/kg体重茶多酚粉末。实验过程中进行一般性指标观测,检测不同阶段4组家兔血脂水平,检测脂肪肝病变程度。结果茶多酚具有降低TC、TG、LDL-C、MDA,升高HDL-C、SOD,降低肝细胞脂肪变性的作用。结论茶多酚可降低动脉粥样硬化兔模型的血脂水平、降低脂肪肝的发生发展。
Objective To investigate the effect of tea polyphenol on rabbit experimental hyperlipidemia and fatty liver.Methods A total of 25 healthy male rabbits were randomly divided into 4 groups（n=5）： control group was given basic diet;model group were given high fat diet;tea polyphenol group was given high fat diet and fed ntragastrically with a dose of 200 mg/kg body weight of tea polyphenol powder at the same time.Results The tea polyphenol could lower TC,TG,LDL-C,MDA,increase HDL-C,SOD,and reduce the role of fatty degeneration of liver cells.Conclusion The tea polyphenol can reduce the lipid level and the occurrence and development of fatty liver in atherosclerotic rabbit model.
出处
《今日药学》
CAS
2010年第5期19-21,共3页
Pharmacy Today
关键词
茶多酚
脂肪肝
兔
tea polyphenol
fatty liver
rabbit
