健康成人血清和唾液中丙二醛含量相关性的研究

The correletion of MDA content in serum and saliva of healthy adults

目的:研究不同年龄段健康成人血清、唾液中丙二醛(malondialdehyde,MDA)含量的变化,及两者含量的相关性。方法:健康成人120名,分为20-39岁、40-59岁、60-79岁、80岁以上4组。用硫代巴比妥酸比色法测定血清和唾液中MDA的含量。结果:(1)20-39岁组血清、唾液中MDA含量显著低于60-79岁组及80岁以上组(p<0.05),20-39岁组与40-59岁组MDA的含量无显著性差异(p>0.05);(2)唾液与血清中MDA的含量存在相关性,(r=0.79,p<0.05)。结论:(1)血清和唾液中的MDA含量随年龄的增长,不断升高;(2)唾液的检测可大体上反映血清中MDA的含量。

Objective：To study age-related changes of the malondialdehyde contents of the saliva and the serum in healthy adults.Methods：120 healthy adults were divided into four groups：20-39 years, 40-59 years, 60-79 years and 80 years and over.The MDA contents of the saliva and the serum in healthy adults were determined using MDA kit.Results：（1）The malondialdehyde contents of the saliva and serum in 20-39 years were significantly lower than that in 60-79 years and 80 years and over groups（p〈0.05）.20-39 years and 40-59 years groups were not significantly different（p〉0.05）.（2） There is distinguished dependability in serum and saliva（r=0.79, p〈0.05）.Conclusion：（1）The malondialdehyde contents of the serum and the saliva of healthy adults decrease with aging.（2）The detection of the saliva can reflect that of the serum.