中西药治疗病毒性心肌炎疗效观察

Effect analysis of integrated traditional Chinese and Western medicine on viral myocarditis

目的观察中西药治疗病毒性心肌炎的疗效。方法选择病毒性心肌炎患者50例,随机分为对照组和治疗组,各25例。治疗组应用炙甘草汤加减合并西药治疗;对照组单纯西药治疗,比较2组临床疗效。结果治疗组总有效率为92.0%明显高于对照组的64.0%,差异有统计学意义(P<0.05)。治疗组治疗后天冬氨酸氨基转移酶(AST)、肌酸激酶(CK)、肌酸激酶同功酶(CK-MB)、乳酸脱氢酶(LDH)及α-羟丁酸脱氢酶(α-HBDH)均较治疗前降低,且低于对照组,差异均有统计学意义(P<0.05或P<0.01)。治疗后2组LVE值均较治疗前升高,且治疗组高于对照组,差异有统计学意义(P<0.05或P<0.01)。治疗组心电图恢复率为80.0%高于对照组的48.0%,差异有统计学意义(P<0.05)。结论中西药治疗病毒性心肌炎患者疗效佳,无不良反应,建议临床推广应用。

Objective To observe the effect of integrated traditional Chinese and Western medicine on viral myocardi- tis. Methods Selected 50 patients with viral myocarditis were randomly divided into control group and treatment group,25 cases each. Treatment group treated with fried glycyrrhizae decoction combined western medicine;Tbe control group treated only with western medicine. When after 2 courses of treatment, compared the clinical efficacy between these 2 groups. Results The total effective rate of treatment group was 92.0% higher than 64.0% in control group, the difference was statistically signifi- cant （ P 〈 0.05 ）. When after treatment the aspartate aminotransferase （ AST）, ereatine kinase （ CK）, creatine kinase isoenzyme （CK-MB） ,lactic dehydrogenase （LDH）and ct-hydroxybutyrate dehydrogenase （ct-HBDH）of treatment group were lower than before,and lower than that in control group, the differences were statistically significant （P 〈 0.05 or P 〈 O. 01 ）. After treat- ment,the LVE values of these two groups were higher than before, and treatment group was higher significantly （ P 〈 0.05 or P 〈0. 01 ）. ECG recovery rate in treatment group was 80.0% higher than 48.0% in control group,the difference was statisti- cally significant（P 〈 0.05）. Conclusion Integrated treatment of viral myocarditis patients has good effect, no adverse reactions, proposal popularized in clinical.