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高血压患者左心室暂时缺血性扩张的临床意义

Clinical implications of transient left ventricular ischemic dilation without coronary artery disease in hypertension
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摘要 目的:核素心肌显像出现的左心室暂时缺血性扩张(TID)与多支冠脉病变及严重冠心病相关。高血压患者核素心肌显像经常出现TID,其临床意义有待深入研究。方法:从508例进行99Tcm-MIBI静息-负荷心肌灌注显像的连续检查者中,根据运动负荷试验指标选择高血压且核素显像与冠脉造影结果均正常的患者35例。同时筛选出25例没有高血压、冠脉造影及核素心肌显像正常的检查者作为对照组。记录核素显像计算机软件同步处理得出的TID数值,并进行随访。结果:高血压组与对照组中TID数值分别为1.09±0.12和0.97±0.08,经统计学研究发现高血压组与对照组对比有显著性差异(t=-4.492,P〈0.01)。高血压组与对照组对比,TIDROC曲线下面积为0.814(P〈0.01,Area=0.5)最佳截点值为1.03(0.693-0.903,95%可信区间)。敏感性77.1%,特异性97.0%。对高血压组和对照组随访(随访时间18-42个月),两组患者均未有严重心脏事件(非致死性心梗和心源性死亡)发生。结论:高血压患者核素心肌显像会出现左心室TID,TID辅助判断冠心病平衡型心肌缺血时应与高血压的影响相鉴别。
出处 《中国临床医学影像杂志》 CAS 北大核心 2010年第5期361-363,共3页 Journal of China Clinic Medical Imaging
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参考文献6

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