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棘状秃发性毛囊炎 被引量：2

Folliculitis spinulosa decalvans:a first case report in China
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摘要 报告1例棘状秃发性毛囊炎。患者男,27岁。因头皮起毛囊性丘疹伴脱发7年就诊。皮肤科检查:头皮片状不规则脱发,有萎缩性瘢痕,头皮、面部、颈部、躯干、四肢广泛分布粟粒大毛囊性丘疹。组织病理检查可见角化过度,表皮萎缩变薄,真皮内胶原纤维增生,呈瘢痕样改变,部分毛囊破坏,周围淋巴细胞、浆细胞及多核巨细胞浸润,符合棘状秃发性毛囊炎改变。 A 27-year-old man presented follicular papulae and alopecia on the scalp for 7 years. Physical examination revealed patched alopecia and atrophic scar on the scalp, generalized follicular papulae distributed on scalp, face, neck, trunk and extremities. Biopsy of the papula showed hyperkeratosis and atrophic epidermis, collagen fiber hyperplasia in dermis seeming to be scar tissue. The hair follicle was partially destroyed with the infiltration of a few lymphocytes, plasmocytes and multinucleated giant cells around the follicles. The diagnosis was folliculitis spinulosa decalvans.
作者 王震英 张磊 陈浩 薛燕宁 孙建方
机构地区 中国医学科学院、北京协和医学院皮肤病研究所
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2010年第5期269-270,共2页 Journal of Clinical Dermatology
关键词 毛囊炎 秃发性 棘状 folliculitis decalvans spinulosa
分类号 R758.71 [医药卫生—皮肤病学与性病学]
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参考文献7

  • 1Oranje AP,van Osch LD,Oosteiwijk JC.Keratosis pilaris atrophicans.One heterogeneous disease or a symptom in different clinical entities?[J].Arch Dermatol,1994,130(4):500-502.
  • 2Di Lernia V,Ricci C.Folliculitis spinulosa decalvans:an uncommon entity within the keratosis pilaris atrophicans spectrum[J].Pediatr Dermatol,2006,23(3):255-258.
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  • 4Gimelli G,Giglio S,Zuffardi O,et al.Gene dosage of the spermidine/spermine N (1)-acetyltransferase (SSAT) gene with putrescine accumulation in a patient with a Xp21.lp22.12 duplication and keratosis follicularis spinulosa decalvans (KFSD)[J].Hum Genet,2002,111(3):235-241.
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同被引文献9

  • 1Romine KA,Rothschild JG,Hansen RC.Cicatricial alopecia and keratosis pilaris.Keratosis follicularis spinulosa decalvans.Arch Dermatol,1997,133(3):381-384.
  • 2Di Lernia V,Ricci C.Folliculitis spinulosa decalvans:an uncommon entity within the keratosis pilaris atrophicans spectrum.Pediatr Dermatol,2006,23(3):255-258.
  • 3Kunte C,Loeser C,Wolff H.Folliculitis spinulosa decalvans:successful therapy with dapsone.J Am Acad Dermatol,1998,39(5 Pt 2):891-892.
  • 4Hallai N,Thompson I,Williams P,et al.Folliculitis spinulosa decalvans:failure to respond to oral isotretinoin.J Eur Acad Dermatol Venereol,2006,20(2):223-224.
  • 5Oosterwijk JC,van der Wielen M J,van de Vosse E,et al.Refinement of the localisation of the X linked keratosis follicularis spinulosa decalvans (KFSD) gene in Xp22.13-p22.2.J Med Genet,1995,32(9):736-739.
  • 6Gimelli G,Giglio S,Zuffardi O,et al.Gene dosage of the spermidine/spermine N (1)-acetyltransferase (SSAT) gene with putrescine accumulation in a patient with a Xp21.1p22.12 duplication and keratosis follicularis spinulosa decalvans (KFSD).Hum Genet,2002,11(3):235-241.
  • 7Sureshbabu R,Kumari R,Ranugha S,et al.Phenotypic and dermatological manifestations in Down Syndrome.Dermatol Online J,2011,17(2):3.
  • 8石秀艳,马东来,方凯.棘状秃发性毛囊炎[J].临床皮肤科杂志,2010,39(8):477-479. 被引量：2
  • 9马东来,石秀艳,方凯.棘状秃发性毛发角化病[J].临床皮肤科杂志,2011,40(6):340-342. 被引量：3

引证文献2

临床皮肤科杂志
2010年 第5期

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