微生态与阴道炎的诊治进展

Treatment Progress of Microecology and Vaginitis

阴道是女性人体重要的微生态区。正常情况下,是以乳酸杆菌等优势菌群为主要的微生态,微生态主要受菌群及机体免疫反应因素的影响,机体免疫反应一定程度上反应了菌群的致病性,并受神经内分泌免疫网络调节。微生态学的发展使人们认识到人体微生态的复杂性,并提出了微生态平衡理论。也逐步改变和更新抗感染的策略,提出单纯"杀菌"转向"杀菌"同时需"促菌"的治疗新观念。当阴道的微生态和免疫功能平衡被破坏易引起阴道炎症。阴道炎根据其病因和病原体的不同有十余种之多。现就常见阴道炎的治疗及其进展进行综述,并对阴道炎治愈标准及治疗后复发及预防再发等相关问题进行讨论。

[Objectives]Vagina is an important microecology zone of female.Under normal condition,the microecology is mainly composed of Lactobacillus and other dominant microflora,microecology is influenced by bacterial flora and immune response factors.The immune response reflects pathogenicity of bacterial flora to a certain extent,and it is regulated by nerve-incretion-immunity network.The development of microecology indicated the complexity of microecology,and microecology balance theory is put forward subsequently.The strategy of anti-infection is improved and updated gradually,and the new therapeutic concept is proposed,which ＂purely sterilization＂ is replaced by ＂sterilization with promoting bacteria＂.When the microecology of vagina and the balance of immune function have been destroyed,it is likely to incur the inflammations of the vagina.According to different causes and pathogens,there are more than ten kinds of vaginitis.The paper generalizes the treatments of vaginitis and their developments,and discusses the cure standard of vaginitis,recurrence and prevention of recurrences.