河北省2004年-2007年麻疹/风疹实验室网络检测结果分析

Analysis on surveillance results of measles and rubella network in Hebei Province from 2004 to 2007

目的:评价2004年-2007年河北省麻疹/风疹实验室网络在加速麻疹和风疹控制中的作用。方法:对2004年-2007年河北省麻疹/风疹网络检测结果和数据进行汇总和分析。结果:2004年-2007年,河北省麻疹监测系统共报告麻疹疑似病例21328例,实验室检测17552份麻疹疑似病例血清,实验室诊断率81.52%(17386/21328),麻疹IgM抗体阳性率为60.04%,检测风疹IgM抗体6475份血清,风疹IgM抗体阳性率为17.13%;诊断风疹暴发43起,暴发病例风疹IgM抗体阳性率为67.07%;省对市级实验室盲样血清考核检测结果符合率为98.37%,标本复核结果符合率为93.11%;国家实验室对省级实验室盲样考核和标本复核符合率每年均为100%正确;分离到麻疹病毒64株,麻疹病毒基因型变化发生了从H1c到H1a和H1b,再到H1a转变,分离到的麻疹病毒分布于我省11个地区;分离到风疹病毒1株。结论:河北省麻疹/风疹实验室网络在麻疹监测系统中及时提供了大量的科学数据,对于加速麻疹和风疹控制和消除发挥了重要作用。

Objective：To evaluate the effect of measles and rubella laboratory network in speeding up measles and rubella control from 2004 to 2007.Methods：We analyzed the data of the measles and rubella network during 2004～2007.Results：From 2004 to 2007,the measles surveillance system reported 21328 cases.The laboratory network had detected 17552 sera of the cases.The rate of laboratory detected cases is 81.52%（17386/21328）.The positive rate of the measles IgM antibody is 60.04%.The laboratory had detected 6475 sera of rubella IgM antibody,and the positive rate of the rubella IgM antibody is 17.13%.The laboratory had detected sera of 43 times rubella breaking out,and the rate of rubella IgM antibody is 67.07%.During 2004～2007,the municipal measles and rubella laboratory network deteced 674 blind sera specimen,the identical rate is 98.37%.After the provincial laboratory detected 972 sera specimen repeatedly,the identical rate is 93.11%.Checked by national measles and rubella laboratory,the provincial laboratory got 100 marks each year from 2004 to 2007.We isolated 64 measles viruses coming from 11 districs,the measles viruses genotype changed from H1c to H1a and H1b,and then to H1a.We got 1 rubella virus the genotype of which is 1E.Conclusion：Hebei provincial measles and rubella laboratory network provided mass sciectific data in measles surveillance system in time,that played very important role in speeding up measles and rubella control.