摘要
为了研究雌二醇对大鼠小肠黏膜IgA+细胞的影响,试验采用免疫组化LSAB法染色,对不同剂量雌二醇处理的各组Wistar雌性大鼠小肠黏膜IgA+细胞的数量进行了统计。结果表明:与对照组相比,卵巢摘除组大鼠小肠黏膜IgA+细胞的数量显著减少;与卵巢摘除组相比,补充适量的雌二醇后,小肠黏膜IgA+细胞的数量显著增多。结果说明卵巢摘除使大鼠小肠黏膜免疫功能降低,补充适量雌二醇后这种情况可以得到改善。
To explore the effect of estradiol on IgA^＋ cells in small intestine mueosa of the rat, immunohistoehemistry was used in the experiment, and the amount of IgA^＋ cells of female Wistar rats that had been given different dosage of estradiol was calculated. The result showed that com- pared with control group, the IgA^＋ cell number of the rats whose ovary had been removed has increased remarkably while compared with OVX group, the IgA^＋ cell number of the rats that had been given proper dosage of estradiol has increased remarkably. A conclusion, therefore, has been reached that removing ovary can reduce the immunity of small intestine mucosa in rats while giving dosage of estradiol can change the effect for better.
出处
《黑龙江畜牧兽医》
CAS
北大核心
2010年第1期5-6,共2页
Heilongjiang Animal Science And veterinary Medicine
基金
国家自然科学基金项目(3047124730671514)
关键词
雌二醇
IgA+细胞
小肠
Estradiol
IgA^＋ cells
small intestine
