基于文献分析的牛黄解毒片(丸)安全性影响因素及对策研究

Retrospective study of adverse reactions of Niuhuang Jiedu tablet (pill) and risk control based on literature analysis

本研究以国内公开发表的牛黄解毒片(丸)相关不良事件个案病例报告为研究对象,通过数据整理、统计分析,认为导致牛黄解毒片(丸)的安全性相关因素主要为不合理用药和药物因素,并基于此,提出风险控制建议,为临床合理用药提供依据。

In this retrospective study,56 cases of adverse reactions caused by Niuhuang Jiedu tablet（pill）were statistically analyzed in respects of genders,ages,routes of administration,clinical manifestations,etc.We pinpointed that the main factors related to safety problems of Niuhuang Jiedu tablet（pill） are irrational drug use and drug quality,and put forward suggestions for strengthening the surveillance and administration of Niuhuang Jiedu tablet（pill） and improving clinical rational use.