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以细胞因子为靶点的抗哮喘药物研究进展

Progress on anti-asthma agents targeted for cytokine
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摘要 许多细胞因子在哮喘患者的气道慢性炎症与重构过程中起到关键作用,是抗哮喘药物的重要靶点。本文主要介绍了近年来以细胞因子(白细胞介素类、肿瘤坏死因子、嗜酸性粒细胞活化趋化因子)为靶点的抗哮喘药物最新进展和发展趋势,并就近年来涌现出的一些新的抗哮喘药物的研究进展作一综述。 Several cytokines which play key role in asthma patients with chronic inflammation and reconstruction of air duct,are important targets for anti asthma agents. In this review, we summarize the latest advancement of antiasthma agents which targeted for cytokines（interleukins, TNF, eotaxin） and investigation development of new anti-asthma agents emerged in recent years.
作者 蔡鑫君 张相彩 徐颖颖
机构地区 浙江省中西医结合医院药剂科
出处 《中国临床药理学与治疗学》 CAS CSCD 2010年第3期350-355,共6页 Chinese Journal of Clinical Pharmacology and Therapeutics
关键词 哮喘 细胞因子 药物治疗 Asthma Cytokine Drug therpy
分类号 R562 [医药卫生—呼吸系统]
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参考文献34

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中国临床药理学与治疗学
2010年 第3期

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