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视神经脊髓炎诊断进展

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摘要 视神经脊髓炎(NMO)是一种常见于亚洲人群,以反复发作,主要累及中枢神经系统(视神经和脊髓)的水通道蛋白(AQP-4)自身免疫病。血清AQP-4抗体既是特异性诊断标志物,也与NMO发病,严重程度有关。针对NMO-IgG自身抗体检测技术进展迅速。
出处 《国际神经病学神经外科学杂志》 2010年第2期148-150,共3页 Journal of International Neurology and Neurosurgery
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  • 1Lennon VA, Wingerchuk DM, Kryzer TJ, et al. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet, 2004, 364 (9451) : 2106- 2112.
  • 2Lennon VA, Kryzer TJ, Pittock SJ, et al. IgG marker of optic-spinal muhiplesclerosis binds to the aquaporin-4 water channel. J Exp Med, 2005, 202(4) : 473-477.
  • 3Lu M, Lee MD, Smith BL, et al. The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain. PNAS, 1996, 93(20) : 10908-10912.
  • 4Rash JE, Yasumura T, Hudson CS, et al. Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord. PNAS, 1998, 95(20) : 11981-11986.
  • 5Tani K, Mitsuma T, Hiroaki Y, et al. Mechanism of Aquaporin-4' s Fast and Highly Selective Water Conduction and Proton Exclusion. J Mol Biol, 2009, 389 (4): 694- 706.
  • 6Hinson SR, McKeon A, Lennon VA. Neurological autoimmunity targeting aquaporin-4. Neuroscience, doi : 10. 1016/ j. neuroscience. 2009.08. 032.
  • 7Takahashi T, Fujihara K, Nakashima I, et al. Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre. Brain, 2007, 130 ( 5 ) : 1235- 1243.
  • 8Kinoshita M, Nakatsuji Y, Kimura T, et al. Neuromyelitis optica: Passive transfer to rats by human immunoglobulin. Biochem Biophys Res Commun, 2009, 386 (4): 623- 627.
  • 9Saadoun S, Waters P, Bell BA, et al. Intra-cerebral injection of neuromyelitis optica immunoglobin G and human complement produces neuromyelitis optica lesions in mice. Brain, 2010, 133(2) :349-361.
  • 10Pittock SJ, Lennon VA, Krecke K, et al. Brain abnormalities in neuromyelitis optica. Arch Neurol, 2006, 63 ( 3 ) : 390-396.

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