摘要
采用氧化解聚法制备改性壳聚糖,并进行纳米化处理,得到纳米改性壳聚糖,将其作为抗菌剂,以天然胶乳为基材,采用共混法制得具有抗菌性能的医用抗菌胶乳。经扫描和透射电镜分析可知:壳聚糖微粒均匀分布在胶乳中,呈圆球状,粒径约为10nm,改性壳聚糖微粒均匀分散在胶乳中;以大肠杆菌作为试验菌,采用抑菌环试验对制得的抗菌胶乳进行抗菌性能的检测,结果表明:抑菌环直径大于抑菌标准规定的7 mm,表明该抗菌胶乳对大肠杆菌的抑菌效果良好。
A nano-modified chitosan was prepared by oxidation methodology and nanotechnology.Medical antibacterial latex was prepared using the nano-modified chitosan as antibacterial agent and natural latex by mechanical blending method.The microstructure of the medical antibacterial latex was studied by scanning electron microscopy（SEM） and transmission electron microscopy（TEM）.The results show that chitosan particles are spherical with particle size of 10 nm and are evenly dispersed in latex matrix.The antibacterial property against Escherichia coli of medical antibacterial latex was tested.The result indicates the antibacterial medical latex has well antibacterial property,with the inhibition ring’s diameter far more than 7 mm.
出处
《材料热处理学报》
EI
CAS
CSCD
北大核心
2010年第5期36-39,共4页
Transactions of Materials and Heat Treatment
基金
山西省科技攻关计划(2007g45)
关键词
纳米
壳聚糖
抗菌
胶乳
共混
nanometer
chitosan
antibacterial
latex
blending
