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达那唑联合环孢素A治疗成人难治性特发性血小板减少性紫癜20例 被引量:3

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摘要 目的观察达那唑联合环孢素A治疗成人难治性特发性血小板减少性紫癜(ITP)的临床疗效。方法选择符合难治性ITP诊断标准的20例患者,给予达那唑300 mg/d,分3次口服;环孢素A 3~4 mg/(kg.d),分3次口服,联合应用3个月,判定疗效。结果显效9例(45%),良效5例(25%),进步2例(10%),无效4例(20%),总有效率为80%。结论达那唑联合环孢素A能有效治疗成人难治性ITP。
出处 《临床医学》 CAS 2010年第5期51-52,共2页 Clinical Medicine
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  • 1Young NS.Autoimmunity and its treatment in aplastic anemia.Am Intern Med,1997,126(2):166-168.
  • 2Sanna V, Di Giacomo A, l.a Cava A, et al. Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses. J Clin Invest, 2003,111:241.
  • 3Martin Romero C, Santos-Alvarez J, Gobema R, et al. Human leptin enhances activation and proliferation of human circulaling T lymphoeytes. Cell Immunol, 2000,199: 15.
  • 4Yang R, Han ZC. Pathogenesis and management of chronic idiopathic thrombocytopenic purpura: an update. Int J Hematol,2000, 71:18.
  • 5Cines DB,Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med,2002,346:995.
  • 6Zhou B, Zhao H, Yang RC, et al. Multi dysfunctional pathophysiology in ITP. Crit Rev in Oncol/Hematol,2005, 54:107.
  • 7Kuwana M, Kaburaki J, Kitasato H, et al. Immunodominant epitopes on glycoprotein IIb-IIIa recognized by autoreactive T cells in patients with immune thrombocytopenic purpura. Blood,2001,98: 130.
  • 8Wardemann H, Yurasov S, Schaefer A, et al. Predominant autoantibody production by early human B cell precursors. Science,2003,301 : 1374.
  • 9Binstadt BA, Geha RS, Bonilla FA. IgG Fe receptor polyrnorphisms in human disease: implications for intravenous immunoglobulin therapy. J Allergy Clin Immunol, 2003,111:697.
  • 10Carcao MD, Blanchette VS, WakefieLd CD, et al. Fegamma receptor IIa and IIIa polymorphisms in childhood immune thrombocytopenic purpura. Br J Haematol,2003,120:135.

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