1例使用10%脂肪乳丙泊酚带入过多脂肪导致患者肝功能恶化的病案分析

Excessive fat infusion worsens liver function after infusing propofol in 10% fat emulsion:one case report

目的:提醒肝功能不全的患者治疗时要特别注意脂肪乳作为赋形型的药物可能导致肝功能负担。方法:通过1例重症胰腺炎患者停用500 mL.d-110%脂肪乳丙泊酚镇静后的相关生化检查情况分析。结果:停用10%脂肪乳丙泊酚后,其AST和ALT好转。结论:肝功能不全患者摄入过多脂肪会加重其肝功能负担。

Objective：To report one case of excessive fat emulsion infusion-induced liver dysfunction.Methods： In the patient with severe acute pancreatitis,biochemical analysis was performed after withdrawal of propofol infusion in 10% fat emulsion（500mL per day） for sedation.Results： After withdrawal of the infusion,abnormal levels of AST and ALT were improved.Conclusion： In the patients with liver insufficiency,excessive intake of fat may worsen liver function.