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急性心肌梗死心肺复苏后溶栓治疗临床价值探讨 被引量:3

Clinical evaluation of thrombolytic therapy after cardiopulmonary resuscitation in patients with acute myocardial infarction
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摘要 目的:探讨急性心肌梗死心肺复苏后溶栓治疗的安全性及临床价值。方法:选择7例急性心肌梗死并心肺复苏后溶栓治疗的患者,分析其冠脉再通率、自主循环恢复率、急性期死亡率、出院生存率、重要脏器出血的发生率、脑复苏的成功率等。结果:对于急性心肌梗死并心肺复苏后的患者,在排除急性心包填塞、胸腹腔出血、继发性颅内出血后给予及时溶栓开通冠脉,能提高患者的自主循环恢复率、出院生存率、降低急性期死亡率,重要脏器出血的发生率无明显提高;对于发病年龄较轻、心肺复苏时间<10 min的患者,脑复苏的成功率较高。结论:急性心肌梗死心肺复苏后溶栓治疗是安全有效的。 Objective:To investigate the clinical value and security of thrombolytic therapy after cardiopulmonary resuscitation(CPR) in patients with acute myocardial infarction(AMI).Method: Thrombolytic therapy was performed in 7 patients with AMI and CPR.The coronary artery recanalization,circulation recovery,vital organ bleeding,cerebral resuscitation,survival rate and mortality were analyzed.Result:After excluding cardic tamponade and acute internal hemorrhage,the thrombolytic therapy performed in time increased the circulation recovery and survival rate and also can reduce mortality rate.While it did not increase the rate of vital organ bleeding.The success rate for cerebral resuscitation was higher in those!young patients with less than 10 minutes for CRP.Conclusion:Thrombolytic therapy in curing the patients with AMI and CPR is safe and effective.
出处 《临床急诊杂志》 CAS 2010年第2期88-90,共3页 Journal of Clinical Emergency
关键词 心肌梗死 心肺复苏 溶栓 疗效 myocardial infarction cardiopulmonary resuscitation thrombolytic curative effect
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  • 1急性心肌梗塞溶栓疗法参考方案(1996年7月修订)[J].中华心血管病杂志,1996,24(5):328-329. 被引量:1321
  • 2SHDRRY S,BELL W R,DUCKET F H,et al.Thrombosis:a national institutes of health consensus development conference[J].Ann Intern Med,1980,93:141-144.
  • 3GUNNAV R M,PASSAMANI E R,BOURDILLON P D V,et al.Guidelines for the early management of patients with acute myocardial infarction[J].J Am Coll Cardial,1990,16:249-292.
  • 4SPANLDING C M,JOLY L,ROSENBERG I,et al.Immediate coronary angiography in survivors of out-of hospital cardiac arrest[J].N Eng J Med,1997,23:1629-1633.
  • 5FISCHER M,BOTTIGER B W,POPOV-CENICS,et al.Thrombolysis using plasminoger activator and heparin reduces cerebral no-reflow after resuscitation from cardiac arrest:an experimental study in the cat[J].Intens Care Med,1996,22:1214-1223.
  • 6KURKCIYAN L,MEMN G,STEAX F,et al.Major bleeding complications after cardiopulmonary resuscitation:impact of thrombolytic treatment[J].J Intern Med,2003,253:128-135.
  • 7SCHREIBER W,GABRIEL D,STERZ F,et al.Thrombolytic therapy after cardiac arrest and its effcct on neurological outcome[J].Resuscitation,2002,52:63-69.
  • 8SCHOLZ K H,TEBBE U,HURMANN C,et al.Frequency of complication of cardiopulmonary resuscitation after thrombolysis during acute myocardial infarction[J].Am J Cardiol,1992,69:724-728.
  • 9VAN KAMPENLC M C,VAN LEEUWEN R,VERHEUGTHF W A.Safety and efficacy of thrombolysis for acute myocardial infarction in patients with prolonged out of hospital cardiopulmonary resuscitation[J].Am J Cardiol,1994,73:953-955.
  • 10CROSS S J,LEE H S,RAWLES J M,et al.Safety of thrombolysis in association with cardiopulmonary resuscitation[J].Br Med J,1991,303:1242-1244.

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  • 1惠波,党群,金喆,夏大胜,王小飞,高陆,蔡林,张靖,王佩显.冠状动脉梗死相关病变钙化与临床表现的关系[J].临床心血管病杂志,2005,21(3):147-149. 被引量:7
  • 2徐泽升,宋志远,马增才,彭万忠,曹绪芬,高巍,韩立宪.急性心肌梗死心肺复苏后冠状动脉内支架治疗[J].临床心血管病杂志,2005,21(7):433-433. 被引量:4
  • 3栗金军,赵丽.急性心肌梗死心肺复苏后急诊重组组织型纤溶酶原激活剂溶栓抢救[J].中西医结合心脑血管病杂志,2006,4(12):1093-1095. 被引量:4
  • 4CHEN M M,LAM A,ABRAHAM J A,et al. CTGF expression is induced by TGF beta in cardiac fibro- blasts and cardiac myocytes: a potential role in heart fibrosis[J]. J Mol Cell Cardiol,2000,32: 1805-1819.
  • 5YAMASHIRO T, FUKUNAGA T, KOBASH1 N, et al. Mechanical stimulation induces CTGF expression in rat osteocytes[J]. J Dent Res,2001,80:461-465.
  • 6VAN AIRMEN G C, VERHESEN W, VAN LEEU WEN R E, et al. MicroRNA-18 and microRNA 19 regulate CTGF and TSP 1 expression in age related heart failure[J]. Aging Cell, 2011,10 :769 - 779.
  • 7SEINO Y, OGAWA A, YANMASHITA T, et al. Ap- plication of NT proBNP and BNP measurements in cardiac care: a more discerning marker for the detec- tion and evalution of heart failure[J]. Eur J Heart Failure, 2004,6:295- 300.
  • 8KOITABASHI N, ARAI M, KOGURE S, et al. In creased connective tissue growth factor relative to brain natriuretic peptide as a determinant of myoeardi al fibrosis[J]. Hypertension,2007,49 :1120- 1127.
  • 9OHNISHI H, OKA T, KUSACHI S, et al. Increased expression of connective tissue growth factor in the in farct zone of experimentally induced myocardial infarc- tion in rats[J]. J Mol Cell Cardiol, 1998,30: 2411- 2422.
  • 10ALMENAR-BONET L, MARTINEZ-DDZ I.. Natri uretie peptidesin heart failure[J]. Rev Esp Cardiol, 2006,6(Suppl F) :15-26.

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