阿尔茨海默病与帕金森病智力与记忆功能的对照分析

Comparative analysis on intelligence and memory of patients with Alzheimer＇s and Parkinson＇s diseases

目的比较阿尔茨海默病（AD）与帕金森病（PD）的智力与记忆功能。方法采用韦氏成人智力量表及韦氏记忆量表对23例AD和27例PD病人进行测查，所有数据均采用χ2及t检验进行分析处理。结果智力方面，AD病人的知识、领悟、算术、相似性、数字广度、词汇、图形排列等7项分测验及言语智商、总智商均明显低于PD病人，突出表现在知识、领悟及相似性方面；其他各项分测验差别均无显著性意义（P均〉0.05）。记忆方面，AD病人的定向、累加、再认、视觉再生、联想学习、背数等6项分测验及记忆商均明显低于PD病人，突出表现在定向、累加、视觉再生及背数方面；其他各项分测验差别均无显著性意义（P均〉0.05）。结论AD及PD病人均呈现明显的智力及记忆功能障碍，但AD病人受损更为严重。

Objective To compare the intelligence and memory of patients with Alzheimer＇s disease （AD） and Parkinson＇s disease （PD）. Methods 23 AD patients and 27 PD patients were compared and analyzed by the Wechsler adult intelligence scale and memory scale revised in China. Results AD patients displayed lower scores on information, comprehension, arithmetic, similarity, digit, vocabulary, picture array, and also showed lower VIQ and FIQ as compared with PD patients, especially in informa- tion, comprehension and similarity. AD patients had lower scores on direction, accumlation, recogni- tion, visual reproduction, association study, digit and memory quotient as compared with PD patients, especially in direction, accumulation, visual reproduction and digit. Conclusions Both AD and PD patients showed serious impairment on intelligence and memory. AD patients, however, displayed more serious and extensive impairment.