不同治疗方式对结核性胸腔积液预后的影响效果分析

目的:探讨结核性渗出性胸腔积液治疗方式。方法:以106例中等量以上积液的结核性胸膜炎病人为研究对象。患者按入院先后顺序随机分为三组。A组36例,胸腔置管引流并胸腔内注射微卡(母牛分枝杆菌菌苗);B组39例,单纯置管引流;C组31例,常规胸腔穿刺抽液每周1～2次。三组患者的化疗方案均为2HRZE(S)/4HR。C组口服强的松30mg/日。治疗1个月评价疗效。结果:1个月A组胸液控制率95.3%,显效31例(86.1%),有效3例(8.3%),无效2例(5.6%),6个月总有效率100%;B组胸液控制率91.1%,显效32例(82%),有效4例(10.3%),无效3例(7.7%),6个月总有效率100%;C组胸液控制率66.6%,显效2例(6.5%),有效18例(58.1%),无效11例(35.4%),6个月总有效率83.3%。结论:深静脉导管引流胸腔积液,注药与不注药差异无显著性,但明显优于常规胸穿抽液。

Objective：To investigate the offect of tuberculous exudative pleural effusion treatment. Methods： 106 patients with moderate or more effusion of tuberculous pleurisy. In patients were randomly divided into 3 groups. A group included 36 patients, chest tube drainage and intrapleural injection of micro - card （ Mycobacterium vaccae vaccine） ; B group included 39 cases, simple tube drainage; C group included 31 eases, routine thoracic fluid puncture 1 to 2 times per week . 3 groups of patients with chemotherapy were 2HRZE （ S）/4HR. Cheek one month treatment. Results：month A group of pleural effusion control rate was 95.3% ,effective in 31 cases （86.1%） ,effective in 3 cases （8. 3%）, 2 cases （5. 6%）, 6 months, the total effective rate 100%; B group of pleural effusion control rate of 91.1% were cured,32 cases （82%） ,effective in 4 cases （10.3%） and 3 cases （7.7%） ,6 months,the total effective rate 100% ;C group pleural effusion control rate was 66.6% were cured,2 cases （6. 5% ） , effective in 18 cases （58.1% ）, ineffective in 11 cases （35.4%） ,6 months,total effective rate was 83.3%. Conclusion： while deep venous catheter drainage of pleural effusion, between injection and noninjection there was no significant difference, but obviously superior to conventional chest wearing a pumping fluid.