IL-10基因修饰骨髓间充质干／祖细胞治疗小鼠急性移植物抗宿主病模型的疗效观察及机制研究

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摘要间充质干细胞（MSC）除在造血微环境的形成及造血调控（如促进造血干细胞归巢及定植等）中起重要作用外，近年其免疫学特性也颇受重视。有报道显示MSC可减低移植物抗宿主病（GVHD）发生率及严重程度，但部分Ⅱ期研究与体外及动物实验的结论并不一致。除偏倚因素外，

作者陈峰吴德沛孙爱宁符粤文常惠荣冯宇锋朱子玲朱明清李佩霞陈列松阮长耿

出处《中华血液学杂志》 CAS CSCD 北大核心 2010年第5期338-341,共4页 Chinese Journal of Hematology

基金基金项目：江苏省医学领军人才培养基金（LJ200626）

关键词急性移植物抗宿主病骨髓间充质 IL-10 疗效观察细胞治疗基因修饰造血干细胞归巢模型

参考文献8

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中华血液学杂志

2010年第5期

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