糖尿病视网膜病变的MR研究进展

MRI studies of retinal oxygenation in diabetic retinopathy

视网膜是体内代谢最旺盛的组织器官之一,氧需求量很高。视网膜长期处于低氧状态(如糖尿病眼病)会产生显著的、严重的不良后果,一般认为这是导致视网膜结构或功能不可逆性改变的根本原因。然而,采用传统方法测量视网膜氧张量有多方面的局限性。随着磁共振成像技术的发展,采用MRI进行无创地检测视网膜氧张量变化已成为可能。本文对糖尿病视网膜病变的MR研究进展进行综述。

The function of the retina is sensitive to oxygen tension,and any changes in oxygen perfusion associated with retinal vessel diseases,such as diabetic retinopathy could affect inner retinal oxygen responses （ΔPO2）. However,the application of currently available techniques in measurements of the retinal oxygenation is limited. Recently,with the development of MRI,it is possible to detect ΔPO2 noninvasively,and the effects are satisfactory. The application of MR based measurements of ΔPO2 following the shift from breathing room air were reviewed in this article.