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早期胃癌直径、淋巴结微转移与组织E1AF、MMP-7mRNA表达临床研究

The Relation of the Diameter of Early Gastric Cancer and Lymph Node Micro-metastasis to E1AF,MMP-7mRNA Expression
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摘要 早期胃癌内镜下切除的安全性取决于严格的术前分期、肿瘤直径及有无淋巴结转移。研究证实早期胃癌组织分型、肿瘤直径、淋巴结微转移与E1AF、MMP-7mRNA表达具有相关性,并使其具有侵袭转移的生物行为。根据临床病理特征及相关组织内E1AFmRNA、MMP-7mRNA表达选择治疗方式,以获取更好疗效。 Accuracy and safe of endoscopic therapy in early gastric cancer relies on strict preoperative staging, tumor size and lymph node metastasis. Study proved histotype in early gastric cancer, tumor size, lymph node micro metastasis were associated with the expression of E1AF, MMP-7mRNA and preformed the invasive metastatic biological behavior. The management, according to clinical pathologic feature and the expression E1AFmRNA, MMP-7mRNA in tumor, would improve the therapeutic effect.
出处 《医学与哲学(B)》 2010年第5期58-59,70,共3页 Medicine & Philosophy(B)
关键词 早期胃癌 肿瘤直径 淋巴结微转移 E1AF MMP-7mRNA表达 early gastric cancer, tumor size, lymph node micro metastasis, expression of El AF, MMP-- 7mRNA
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参考文献17

  • 1沈虹,袁瑛,郑树,潘文胜.极微小胃癌临床病理特征及治疗的探讨[J].中华普通外科杂志,2009,24(4):269-272. 被引量:1
  • 2潘文胜 ,陈丽荣,刘颖斌,汪春付 ,王小英 ,仲华.内镜下黏膜剥离术在早期胃癌治疗中的应用一例[J].中华普通外科杂志,2007,22(1):71-72. 被引量:5
  • 3Kawasaki H, Kilayama J, lshigami H, et al. Solitary splenic metastasis from early gastric cancer: report of acase[J].Surg Today, 2010, 1:60 -63.
  • 4Hirasawa T, Gotoda T, Miyata S, et al. Incidence of lymph node metastasis and the feasibility of endoscopic resection for undifferentiated early gastric cancer[J]. Gastric cancer, 2009, 12: 148- 152.
  • 5Jeong Won Kim, Ilseon Hwang, Mi Jung Kim, et al. Clinicopathological characteristics and predictive markers of Early gastric cancer with recurrence[J].J Korean reed sci, 2009, 24: 1158- 1164.
  • 6Higashino F, Yishida K, Noumi T, et al. Ets-related protein EIAF can active 3 different matrix metalprotienase gene promoters [J]. Oncogene, 1995, 10:1461- 1463.
  • 7Kitoh T, Yanani H, Saitoh Y, et al. Increased expression of ma trix metalloproteinase- 7 in invasive early gastric cancer[J].J Gastroenterol, 2004, 39(5):434-440.
  • 8Hirasaki S, Tanimizu M, Moriwaki T. Efficacy of clinical pathway for the management of mucosal gastric carcinoma treated with endoscopic submucosal disseclion using an insulated- tip diathermic knife[J]. Intern Med, 2001,43(12): 1120-1125.
  • 9Lee K H, Shin S J, Kim K O,et al. Relationship between E-cadherin, matrix metalloproteinase 7 gene expression and clinicopathological features in gastric carcinoma [J]. Oncol Rep, 2006, 16(4): 823- 830.
  • 10Song S Y, Park S, Kim S. Characteristics of intramucosal gastric carcinoma with lymph node metastatic disease[J]. Histopathology, 2004,44(5):437-444.

二级参考文献15

  • 1潘文胜,曹敏.伴淋巴结转移的早期胃癌病理组织形态学研究[J].中华消化杂志,2006,26(2):104-107. 被引量:9
  • 2潘文胜 ,陈丽荣,刘颖斌,汪春付 ,王小英 ,仲华.内镜下黏膜剥离术在早期胃癌治疗中的应用一例[J].中华普通外科杂志,2007,22(1):71-72. 被引量:5
  • 3Peril F, luliano R, Valente G, et al. Minute and small early gastric cancers in a Western population: a clinicopathologic study. Gastrointest Endosc, 1995, 41:475-480.
  • 4Yasuda K, Shiraishi N, Suematsu T, et al. Rate of detection of lymph node metastasis is correlated with the depth of submucosal invasion in early stage gastric carcinoma. Cancer, 1999, 85: 2119-2123.
  • 5滝沢登一郎,小池盛雄,船田信顕,等.胃癌の組織学的多样性と転移、浸润に関する病理形態学的考察.外科治療,1997,77:29-36.
  • 6久保起与子,柳澤照夫,二宮康朗,等.HE染色による胃型分化型腺癌の病理学的特徵.胃と腸,1999,34:487-494.
  • 7西倉健,渡辺英伸,味岡洋一,等.胃型分化型腺癌の判断基準と病理学的特徴.胃と肠,1999,34:495-506.
  • 8Oda I, Saito D, Tada M, et al. A muhicenter retrospective study of endoscopic resection for early gastric cancer. Gastric Cancer, 2006,9:262-270.
  • 9Xu X, Roberts SA, Pasha TL, et al. Undesirable cytokeratin immunoreactivity of native nonepithelial cells in sentinel lymph nodes from patients with breast carcinoma. Arch Pathol Lab Med, 2000, 124(9): 1310-1313
  • 10Okada Y, Fujiwara Y, Yamamoto H, et al. Genetic detection of lymph node micrometastases in patients with gastric carcinoma by multiple-marker reverse transcriptase-polymerase chain reaction assay. Cancer, 2001,92(8): 2056-2064

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