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心外膜脂肪与冠心病关系的研究进展 被引量：7

Research progress in the relation between epicardial adipose tissue and coronary heart disease
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摘要 心外膜脂肪是沉积在心脏周围,特别是围绕在冠状动脉周围的内脏脂肪。心外膜脂肪可合成众多的脂肪细胞因子,通过旁分泌和滋养血管分泌作用于临近的冠状动脉或心脏,影响冠心病的发生发展。对心外膜脂肪及其分泌的脂肪细胞因子的深入研究将为冠心病的防治提供新的关注靶点。 Epicardial adipose tissue is the adipose tissue that deposits on the heart especially the adipose tissue surrounding coronary arteries.Epicardial adipose tissue can synthesize lots of adipokines which act on adjacent coronary artery or heart through paracrine and vasocrine,thus influences occurrence and development of coronary heart disease.So studying epicardial adipose tissue and adipokines secreted by itself thoroughly would provide a new concerned target for prevention and treatment of coronary heart disease.
作者 高秀莹 陶红
机构地区 首都医科大学附属北京安贞医院
出处 《现代生物医学进展》 CAS 2010年第8期1573-1575,1579,共4页 Progress in Modern Biomedicine
关键词 心外膜脂肪 脂肪细胞因子 冠心病 Epicardial adipose tissue Adipocytokine Coronary heart disease
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献24

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二级参考文献5

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共引文献6

同被引文献69

  • 1彭晋,张龙江,卢光明.双源双能量CT心肌灌注成像的应用进展[J].医学研究生学报,2011,24(7):775-779. 被引量：6
  • 2裴强,秦永文,吴弘,郑兴,丁继军.血清脂联素水平与冠状动脉病变程度的关系[J].临床心血管病杂志,2004,20(10):619-621. 被引量：33
  • 3刘岩,邹大进,李慧,陈月,丁继军,郑兴,郭鹏飞.低脂联素血症是冠状动脉粥样硬化严重程度的重要标志[J].中华内分泌代谢杂志,2005,21(1):5-8. 被引量：111
  • 4李敬伟,党群.脂联素与冠心病关系的研究进展[J].中国心血管杂志,2007,12(3):224-226. 被引量：2
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  • 6Baker AR,Silva NF,Quinn DW,et al.Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease [ J ].Cardiovasc Diabetol,2006,5:1.
  • 7Iacobellis G,Pistilli D,Gucciardo M,et al.Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease [ J ].Cytokine,2005,29(6):251-255.
  • 8Ahn SG,Lim HS,Joe DY,et al.Relationship of epicardial adipose tissue by echocardiography to coronary artery disease [ J ].Heart,2008,94(3):e7.
  • 9Jeong JW,Jeong MH,Yun KH,et al.Echocardiographic epicardial fat thickness and coronary artery disease [ J ].Cite J,2007,71(4):536-539.
  • 10Spiroglou SG,Kostopoulos CG,Varakis JN,et al.Adipokines in periaortic and epicardial adipose tissue:differential expression and relation to atherosclerosis [ J ].J Atheroscler Thromb,2010,17(2):115-130.

引证文献7

二级引证文献21

现代生物医学进展
2010年 第8期

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