摘要
目的建立HPLC法测定头孢氨苄胶囊含量的不确定度分析的方法。方法通过建立HPLC法测定数学模型,找出影响不确定度的因素,并对各个不确定度分量进行评定,计算各变量的不确定度,由此计算合成不确定度,最终给出测量结果的扩展不确定度和置信水平。结果计算各分量的相对标准不确定度,由此计算合成不确定度及扩展不确定度(P=95%,K=2)。结论建立的不确定度计算方法可用于HPLC法测定头孢氨苄胶囊含量的不确定度的分析。
Objective To estabhsh a HPLC method for unce^ainty analysis of Cefalexin Capsules. Methods The calculation formula of uncertainty was deduced in the procedure of determination the content in Capsules.Each active components of uncertainty was calculated the variable parameters among the procedures. The combined uncertainty and extended uncertainty and confidence was finally obtained by synthesized the uncertainties of various component variables. Results The mathematic model of uncertainty is establish for applicable to cvaluate the accuracy of assay of puerain injection. Conclusion The mathematic model of uncertainty of measureme establish is reasonable and reliable,it is applicable to evaluate accuracy of assay for the capsules with HPLC.
出处
《中国现代医生》
2010年第14期19-21,共3页
China Modern Doctor
