参麦注射液对烧伤患者外周血T淋巴细胞增殖和白细胞介素2产生的调理作用

Enhancing effect of shenmai injection on peripheral blood lymphocyte proliferation and interleukin-2 production in patients of burn

目的探讨参麦注射液对烧伤患者细胞介导的免疫功能的调理作用。方法用参麦注射液治疗烧伤患者,并测定外周血T淋巴细胞增殖反应和白细胞介素-2（IL-2）产生能力,以判定其疗效。结果用药后5 d外周血T淋巴细胞开始回升,10~20 d增殖反应明显;IL-2产生能力与T淋巴细胞增殖反应一致（P〈0.05或P〈0.01）。结论参麦注射液对烧伤患者细胞介导的免疫功能有调理作用。

Objective To study the regulatory effect of shenmai injection on cell mediated immune function in patients of burn.Methods Patients of burn were treated with shenmai and the therapeutic effect was evaluated by their peripheral blood T lymphocyte（PBL） proliferation and interleukin-2（IL-2） production determination.Results The PBL proliferation began to increase after 5 days of medication and the response was significant between the 10th to 20th day,which was in accordance with the change of IL-2 production.Conclusion Shenmai injection has immune regulatory effect on cell mediated immune function in patients of burn.