老年上消化道出血患者医院感染特点及相关危险因素研究

Nosocomial Infection and Risk Factors in Aged Patients with Upper Gastrointestinal Bleeding

目的探讨老年上消化道出血患者医院感染特点及相关危险因素。方法对2006年1月-2008年12月收治的342例老年上消化道出血患者进行临床调查分析。结果 31例发生医院感染,感染率为9.06%,感染部位以呼吸道感染为主(67.75%),其次为腹腔内组织及胃肠道感染,各占9.68%;病原菌以革兰阴性杆菌为主;导致感染的危险因素依次为住院时间、伴随基础疾病、出血量、侵入性操作及出血病因。结论老年上消化道出血患者医院感染发生率高,临床医务人员应高度重视,采取综合措施加以防治,降低医院感染率。

OBJECTIVE To explore the characteristic of nosocomial infection and the risk factors in aged patients with upper gastrointestinal bleeding. METHODS The prospective clinical investigations were performed in 342 patients whose age were more than 60 years old with upper gastrointestinal bleeding from Jan 2006 to Dec 2008. RESULTS From them 9. 06% of patients suffered nosocomial infection. The infections site was mainly the respiratory tract （67. 75%）, then introabdominal tissues and gastrointestinal test （all 9. 68%）. The main pathogens of nosocomial infection were G-bacilli, the risk factors related to nosocomial infection were hospitalization duration, underlying disease, invasive manipulations, and bleeding amount, bleeding cause. CONCLUSIONS The aged patients with upper gastrointestinal bleeding have high incidence of nosocomial infection. Clinicians should pay more attention to nosocomical infection in aged patients with upper gastrointestinal bleeding and prevent the incidence of nosocomial infection and monitoring the risk factors to decrease the nosocomial infection rate.