外科重症监护病房医院获得性肺炎的细菌耐药分析

Analysis of Bacterial Drug Resistance in ICU Surgical Patients with Hospital Acquired Pneumonia

目的调查医院外科重症监护病房(SICU)医院获得性肺炎(HAP)感染情况,了解主要病原菌的构成与耐药性,为临床合理选用抗菌药物提供依据。方法收集2008-2009年全院符合HAP的患者100例,进行细菌分布和临床特征的调查。结果 SICU HAP革兰阳性病原菌以金黄色葡萄球菌为主(42.5%),其中耐甲氧西林金黄色葡萄球菌占43.8%;革兰阴性菌中不动杆菌属(10.0%)、肺炎克雷伯菌(10.0%)占第1位。结论 SICU HAP主要病原菌为金黄色葡萄球菌、不动杆菌属、肺炎克雷伯菌,加强细菌耐药性监测,合理使用抗菌药物十分重要。

OBJECTIVE To investigate the epidemiology of hospital acquired pneumonia（HAP） in surgical patients admitted to intensive care unit （ICU）, to provide evidence for clinically reasonable administration of antibacterial agents and acquire the composition of pathogenic bacteria and its resistance. METHODS 100 patients with HAP admitted to hospital between 2008 and 2009 were analyzed to get bacteria distribution and clinical characteristics. RESULTS Among gram positive bacteria, Staphylococcus aureus accounted for 42. 5~~0 （methicillin resistant Staphylococcus aureus accounted for 43. 8~）. Among gram negative bacteria, Acinetobacter and Klebsiella ranked the first, which accounted for 10% CONCLUSIONS Staphylococcus aureus, Acinetobacter and Klebsiella are the main bacteria of ICU patients with HAP. It is very important to strengthen the surveillance of bacterial drug resistance and reasonably use the antibacterial agents.