共轭亚油酸的微乳及其性质研究

Study on conjugated linoleic acid microemulsion

制备了共轭亚油酸/EL-35和EL-10/乙醇/水体系的O/W型微乳液。考察了温度、防腐剂和pH对微乳液区域的影响;动态光散射测定了微乳液的粒径;利用粘度计测定不同水含量的微乳液的粘度变化来观察微乳液流变性;对O/W、W/O、B.C.中的共轭亚油酸的微乳液和共轭亚油酸乙醇溶液进行了光稳定性研究,还分析了温度和pH对微乳液和乙醇溶液中共轭亚油酸稳定性的影响。结果表明,温度升高,防腐剂苯甲酸钠浓度变大和pH降低使微乳区稍有减小;微乳液粒径在制备三个月后仍保持在80～90nm之间;共轭亚油酸对光热和酸都比较敏感,但同环境条件下,O/W型微乳液中的共轭亚油酸比较稳定。

An O/W microemulsion that consists of non-ionic surfactant EL-35 and EL-10,cosurfactant ethanol and oil conjugated linoleic acid was developed with pseudo-ternary phase diagram.The influences of temperature, antiseptic as well as the pH on microemulsion areas were also considered.The effects of sunlight on the stability of conjugated linoleic acid were comparatively studied in microemulsion （O/W, W/O B.C.）.The dynamic light scattering （DLS） was used to evaluate the particle diameters. The variation in viscosity in the microemulsion system have been investigated using viscosity measurements ;The effects of pH, high temperatures on the stability of β-Carotene were comparatively studied both in microemulsion and in ethanol solution.The results showed that the microemulsion region decreased slightly with the increase of temperature and the decrease of pH.Antiseptic has hardly influences on the microemulsion regions. The conjugated linoleic acid contained in the O/W microemulsion,was much highly resistant to sunlight, pH and high temperature.