BIPAP无创通气治疗COPD并Ⅱ型呼吸衰竭

Clinical Efficacy of Non-invasive Mechanical Ventilation with BiPAP Ventilator on COPD with Tape Ⅱ Respiratory Failure

目的:探讨双水平无创正压通气(BIPAP)治疗慢性阻塞性肺疾病(COPD)并Ⅱ型呼吸衰竭的临床价值。方法:选择符合应用无创通气指征的COPD并Ⅱ型呼吸衰竭患者,在常规抗感染、解痉、止咳、化痰等治疗基础上应用BIPAP无创通气,观察通气前、通气后4小时及24小时血气分析指标以及心率、呼吸频率的变化。结果:无创通气治疗后PH、PaO_2明显上升,PaCO_2明显降低,心率及呼吸频率明显改善,差异有显著性(P<0.05)。结论:BIPAP无创通气是治疗COPD并Ⅱ型呼吸衰竭经济、有效的方法。

Objective：To evaluate the effects of the BiPAP ventilation on COPD with Tape Ⅱ respiratory failure.Methods：60 Patients with tape Ⅱ respiratory failure by COPD complied with the standard of non-invasive MV.They were treated by conventional therapy such as anti-infection,spasmolysis,dissipating phlegm ,at the same time used BiPAP.Blood gas analysis, heart rate（HR） and respiratory rate（RR） were observed before,4 hours and 24 hours after MV.Results：After non-invasive MV, PH and PaO2 increased,PCO2 decreased,HR and RR decreased（P〈0.05）.Conelusion：Non-invasive MV with BiPAP ventilator is effective on COPD with tape Ⅱ respiratory failure.